Serving size: 2 capsules
Other ingredients: gelatin (bovine), vegetable magnesium stearate, silicon dioxide, rice flour.
Capsules contain bovine gelatin.
Cirillo C, Capasso R. "Constipation and Botanical Medicines: An Overview." Phytother Res. 2015 Oct;29(10):1488-93. doi: 10.1002/ptr.5410. Epub 2015 Jul 14.
Radwan AB, El-Debeiky MS, Abdel-Hay S. "Contrast enema as a guide for senna-based laxatives in managing overflow retentive stool incontinence in pediatrics." Pediatr Surg Int. 2015 Aug;31(8):765-71. doi: 10.1007/s00383-015-3741-9. Epub 2015 Jul 15.
Rama Reddy NR, Mehta RH, Soni PH, Makasana J, Gajbhiye NA, Ponnuchamy M, Kumar J. "Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties." PLoS One. 2015 Jun 22;10(6):e0129422. doi: 10.1371/journal.pone.0129422. eCollection 2015.
Marciniak CM, Toledo S, Lee J, Jesselson M, Bateman J, Grover B, Tierny J. "Lubiprostone vs Senna in postoperative orthopedic surgery patients with opioid-induced constipation: a double-blind, active-comparator trial." World J Gastroenterol. 2014 Nov 21;20(43):16323-33. doi: 10.3748/wjg.v20.i43.16323.
Yenidogan E, Okan I, Kayaoglu HA, Akgul GG, Sansal M, Tali S, Ozsoy Z, Sahin M. "Same-day colonoscopy preparation with Senna alkaloids and bisacodyl tablets: a pilot study." World J Gastroenterol. 2014 Nov 7;20(41):15382-6. doi: 10.3748/wjg.v20.i41.15382.
Feudtner C, Freedman J, Kang T, Womer JW, Dai D, Faerber J. "Comparative effectiveness of senna to prevent problematic constipation in pediatric oncology patients receiving opioids: a multicenter study of clinically detailed administrative data." J Pain Symptom Manage. 2014 Aug;48(2):272-80. doi: 10.1016/j.jpainsymman.2013.09.009. Epub 2013 Dec 8.
http://www.webmd.com/vitamins-supplements/ingredientmono-652-senna.aspx
Marchesi M, Marcato M, Silvestrini C. "[Clinical experience with a preparation containing cascara sagrada and boldo in the therapy of simple constipation in the elderly]." G Clin Med. 1982 Nov-Dec;63(11-12):850-63
Chakŭrski I, Matev M, Koĭchev A, Angelova I, Stefanov G." [Treatment of chronic colitis with an herbal combination of Taraxacum officinale, Hipericum perforatum, Melissa officinaliss, Calendula officinalis and Foeniculum vulgare]." Vutr Boles. 1981;20(6):51-4.
Matev M, Chakŭrski I, Stefanov G, Koĭchev A, Angelov I. "[Use of an herbal combination with laxative action on duodenal peptic ulcer and gastroduodenitis patients with a concomitant obstipation syndrome]." Vutr Boles. 1981;20(6):48-51
BRODERS AC Jr. "Clinical studies with dioctyl sodium sulfosuccinate plus cascara derivative; a new agent for the treatment of constipation." Am J Dig Dis. 1957 Sep;2(9):483-6.
Thompson CE. "A Report of Three Hundred and Five Cases of Habitual and Temporary Constipation Treated with Cascara Sagrada." Br Med J. 1884 Mar 22;1(1212):556.
Lithgow RA. "Cascara Sagrada in Constipation." Br Med J. 1883 Jul 14;2(1176):68
http://www.webmd.com/vitamins-supplements/ingredientmono-773-cascara.aspx
Mehmood MH, Aziz N, Ghayur MN, Gilani AH. "Pharmacological basis for the medicinal use of psyllium husk (Ispaghula) in constipation and diarrhea." Dig Dis Sci. 2011 May;56(5):1460-71. doi: 10.1007/s10620-010-1466-0. Epub 2010 Nov 17.
Wang HJ, Liang XM, Yu ZL, Zhou LY, Lin SR, Geraint M. "A Randomised, Controlled Comparison of Low-Dose Polyethylene Glycol 3350 plus Electrolytes with Ispaghula Husk in the Treatment of Adults with Chronic Functional Constipation.' Clin Drug Investig. 2004;24(10):569-76.
Dettmar PW, Sykes J. "A multi-centre, general practice comparison of ispaghula husk with lactulose and other laxatives in the treatment of simple constipation." Curr Med Res Opin. 1998;14(4):227-33.
Dessau RB, Olsen OB, Frifelt JJ, Skott H. "Influence of psyllium seed husk on azotemia, electrolytes, and bowel regulation in patients on CAPD." Perit Dial Int. 1989;9(4):351.
Kumar A, Kumar N, Vij JC, Sarin SK, Anand BS. "Optimum dosage of ispaghula husk in patients with irritable bowel syndrome: correlation of symptom relief with whole gut transit time and stool weight." Gut. 1987 Feb;28(2):150-5.
http://www.webmd.com/drugs/2/drug-56088/psyllium-husk-fibre-oral/details
Hanif Palla A, Gilani AH. "Dual effectiveness of Flaxseed in constipation and diarrhea: Possible mechanism." J Ethnopharmacol. 2015 Jul 1;169:60-8. doi: 10.1016/j.jep.2015.03.064. Epub 2015 Apr 15.
Ramos CI, Andrade de Lima AF, Grilli DG, Cuppari L. "The short-term effects of olive oil and flaxseed oil for the treatment of constipation in hemodialysis patients." J Ren Nutr. 2015 Jan;25(1):50-6. doi: 10.1053/j.jrn.2014.07.009. Epub 2014 Sep 17.
Xu J, Zhou X, Chen C, Deng Q, Huang Q, Yang J, Yang N, Huang F. "Laxative effects of partially defatted flaxseed meal on normal and experimental constipated mice." BMC Complement Altern Med. 2012 Mar 9;12:14. doi: 10.1186/1472-6882-12-14.
Lee EJ, Warden S. "A qualitative study of quality of life and the experience of complementary and alternative medicine in Korean women with constipation." Gastroenterol Nurs. 2011 Mar-Apr;34(2):118-27. doi: 10.1097/SGA.0b013e3182109405.
http://www.webmd.com/vitamins-supplements/ingredientmono-991-flaxseed.aspx
Cellini L, Di Bartolomeo S, Di Campli E, Genovese S, Locatelli M, Di Giulio M. "In vitro activity of Aloe vera inner gel against Helicobacter pylori strains." Lett Appl Microbiol. 2014 Jul;59(1):43-8. doi: 10.1111/lam.12241. Epub 2014 Mar 25.
Foster M, Hunter D, Samman S. "Evaluation of the Nutritional and Metabolic Effects of Aloe vera." In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 3.
Wintola OA, Afolayan AJ. "Phytochemical constituents and antioxidant activities of the whole leaf extract of Aloe ferox Mill." Pharmacogn Mag. 2011 Oct;7(28):325-33. doi: 10.4103/0973-1296.90414.
Wintola OA, Sunmonu TO, Afolayan AJ. "The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats." BMC Gastroenterol. 2010 Aug 19;10:95. doi: 10.1186/1471-230X-10-95..
Odes HS, Madar Z. "A double-blind trial of a celandin, aloevera and psyllium laxative preparation in adult patients with constipation." Digestion. 1991;49(2):65-71.
http://www.webmd.com/vitamins-supplements/ingredientmono-607-aloe.aspx
Magro DO, de Oliveira LM, Bernasconi I, Ruela Mde S, Credidio L, Barcelos IK, Leal RF, Ayrizono Mde L, Fagundes JJ, Teixeira Lde B, Ouwehand AC, Coy CS. "Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation." Nutr J. 2014 Jul 24;13:75. doi: 10.1186/1475-2891-13-75.
Yoon H, Park YS, Lee DH, Seo JG, Shin CM, Kim N. "Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial." J Clin Biochem Nutr. 2015 Sep;57(2):129-34. doi: 10.3164/jcbn.15-14. Epub 2015 Jun 30.
Choi SC, Kim BJ, Rhee PL, Chang DK, Son HJ, Kim JJ, Rhee JC, Kim SI, Han YS, Sim KH, Park SN. "Probiotic Fermented Milk Containing Dietary Fiber Has Additive Effects in IBS with Constipation Compared to Plain Probiotic Fermented Milk." Gut Liver. 2011 Mar;5(1):22-8. doi: 10.5009/gnl.2011.5.1.22. Epub 2011 Mar 16.
An HM, Baek EH, Jang S, Lee do K, Kim MJ, Kim JR, Lee KO, Park JG, Ha NJ. "Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents." Nutr J. 2010 Feb 5;9:5. doi: 10.1186/1475-2891-9-5.
Drouault-Holowacz S, Bieuvelet S, Burckel A, Cazaubiel M, Dray X, Marteau P. "A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome." Gastroenterol Clin Biol. 2008 Feb;32(2):147-52. doi: 10.1016/j.gcb.2007.06.001. Epub 2008 Mar 4.
http://www.webmd.com/vitamins-supplements/ingredientmono-790-lactobacillus.aspx
Hawrelak JA, Myers SP. " Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study." J Altern Complement Med. 2010 Oct;16(10):1065-71. doi: 10.1089/acm.2009.0090.
Chen G, Zhu L, Liu Y, Zhou Q, Chen H, Yang J. "Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo." Phytother Res. 2009 Apr;23(4):498-506. doi: 10.1002/ptr.2660.
Asano T, Ishihara K, Morota T, Takeda S, Aburada M. "Permeability of the flavonoids liquiritigenin and its glycosides in licorice roots and davidigenin, a hydrogenated metabolite of liquiritigenin, using human intestinal cell line Caco-2." J Ethnopharmacol. 2003 Dec;89(2-3):285-9.
Takagi K, Ishii Y. "Peptic ulcer inhibiting properties of a new fraction from licorice root (Fm100). I. Experiental peptic ulcer and general pharmacology." Arzneimittelforschung. 1967 Dec;17(12):1544-7
http://www.webmd.com/vitamins-supplements/ingredientmono-881-licorice.aspx
Ooi EM, Watts GF, Ng TW, Barrett PH. "Effect of dietary Fatty acids on human lipoprotein metabolism: a comprehensive update." Nutrients. 2015 Jun 2;7(6):4416-25. doi: 10.3390/nu7064416
Mañé J, Pedrosa E, Lorén V, Ojanguren I, Fluvià L, Cabré E, Rogler G, Gassull MA. "Partial replacement of dietary (n-6) fatty acids with medium-chain triglycerides decreases the incidence of spontaneous colitis in interleukin-10-deficient mice." J Nutr. 2009 Mar;139(3):603-10. doi: 10.3945/jn.108.101170. Epub 2009 Jan 6..
Yen HC, Lai WK, Lin CS, Chiang SH. "Medium-chain triglyceride as an alternative of in-feed colistin sulfate to improve growth performance and intestinal microbial environment in newly weaned pigs." Anim Sci J. 2015 Jan;86(1):99-104. doi: 10.1111/asj.12248. Epub 2014 Jul 12.
Bertevello PL, De Nardi L, Torrinhas RS, Logullo AF, Waitzberg DL. "Partial replacement of ω-6 fatty acids with medium-chain triglycerides, but not olive oil, improves colon cytokine response and damage in experimental colitis." JPEN J Parenter Enteral Nutr. 2012 Jul;36(4):442-8. doi: 10.1177/0148607111421788. Epub 2012 Jan 23.
http://www.webmd.com/vitamins-supplements/ingredientmono-915-medium%20chain%20triglycerides%20(mcts).aspx
Returns are accepted within 30 days of purchase. For details, see our Shipping & Returns page.
Q. Does this really work?
A. Based on customer reviews we have a large number of people having positive results with this product. However results will vary as every one is different.
Q. What is the difference between this product and laxatives?
A. Its all natural. If you take 2 capsules with a huge glass of water. It will produce a normal bowel movement when u wake up. No cramping etc. The ingredients are different.
Q. Do you need to alter your diet in any way while doing this cleanse?
A. Here are some tips:
1. Drink lots of Water
2. Eat Plenty of Fiber.
3. Chew Your Food.
Q. Is it safe for my husband to take it when we are trying to be pregnant?
A. We recommend you consult your Ob/Gyn or your healthcare professional.
Q. I'm afraid I will have to be running to the bathroom all day at work. Has anyone had an issue with this?
A. You can take the product right before bed time with a full glass of water, so hopefully when you woke up in the morning, you can go. But everyone's different and our body's act differently. Just an important note, once it does hit you, you will need a bathroom close. Also make sure to drink a lot of water to avoid dehydration.
Q. Do you go throughout the day? Or does it happen all at once?
A. In the very first few days, you may go throughout the day. Sometimes within 1-2 hours after taking a meal. But after the first few days or a week, it should be more like all at once or twice. It really depends.
Q. Do your products contain Gluten?
A. Many of our products use vegetable capsules and so do not contain gluten. However some of our products are manufactured in a facility that processes other products that contain gluten so we can't guarantee there is no trace of gluten in some products. Please refer to the page for the specific product you are interested in for more information.
Q. Are your products safe to use?
A. Our formulas are made in a US cGMP facility. If you are pregnant, nursing, taking medication or have a medical condition, check with your healthcare professional before use.
Q. Can I take your products with prescription medication?
A. Unfortunately, legally, we cannot give you medical advice around taking this product with prescription medicine. So I strongly suggest if you have any questions or concerns about using our product with your current medication or you have a medical condition, then you contact your healthcare professional to see if it will be ok.
Q. Where are your products manufactured?
A. Our products are made in a US cGMP, FDA-registered facility.
Q. When will my product arrive?
A. Standard product delivery time is between 3-5 business days from the time of your order. Priority shipping will be 1-2 days depending on the time of order.
Q. Do you ship internationally?
A. Yes. International shipping is $19.99 per order. Free US shipping on orders of $50 or more ($4.95 under $50).
Q. Can I return a product?
A. Yes, within 30 days of purchase. Email support@nutracraft.com with your order number to start a return. Return shipping is paid by the customer.
Q. Do you have a contact number I can reach you at?
A. Please contact our Customer Support Team at 1-855-377-7444
Just like you, we live everyday determined to improve our bodies and quality of life through better life choices, proper nutrition and supplementing with quality herbs, blends, and vitamins. Regardless of your current level of health, you deserve nutritional supplements that you can trust.
You can rest easy knowing that our supplements are formulated by experts using high-quality natural ingredients in a top-of-the-line, FDA registered facility using Good Manufacturing Practices.
Along with great products, we have unmatched customer service. If you have a question or issue you want to discuss, give us a call, send us an email. We’ll respond properly. We’ll give you the attention that you deserve.
And lastly, we truly care. We care about you and your health. We go that extra mile to make sure that you're well taken care of through education and great products, fast shipping, and amazing customer support.
Shop with us today and feel the Nutracraft difference for yourself.
