Ingredients

• Serrapeptase
• Papain
• Bromelain
• Fungal Protease
• Bacillus subtilis
• Devil's Claw Root Extract (Harpagophytum procumbens)(0.5% Harpagoside)
• Ginger Root Extract (Zingiber officinale)(5% Gingerols)
• White Willow Bark (Salix alba)(30% Salicin)

References

• Joshi KK, Nerurkar RP. "Anti-inflammatory effect of the serratiopeptidase--rationale or fashionable: a study in rat paw oedema model induced by the carrageenan." Indian J Physiol Pharmacol. 2012 Oct-Dec;56(4):367-74.

• Murugesan K, Sreekumar K, Sabapathy B. "Comparison of the roles of serratiopeptidase and dexamethasone in the control of inflammation and trismus following impacted third molar surgery." Indian J Dent Res. 2012 Nov-Dec;23(6):709-13. doi: 10.4103/0970-9290.111243.

• Mazzone A, Catalani M, Costanzo M, Drusian A, Mandoli A, Russo S, Guarini E, Vesperini G. "Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo." J Int Med Res. 1990 Sep-Oct;18(5):379-88.

• Kumar S, Jana AK, Dhamija I, Singla Y, Maiti M. "Preparation, characterization and targeted delivery of serratiopeptidase immobilized on amino-functionalized magnetic nanoparticles." Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):413-26. doi: 10.1016/j.ejpb.2013.06.019. Epub 2013 Jul 10.

• Viswanatha Swamy AH, Patil PA. "Effect of some clinically used proteolytic enzymes on inflammation in rats." Indian J Pharm Sci. 2008 Jan;70(1):114-7. doi: 10.4103/0250-474X.40347.

• http://www.webmd.com/vitamins-supplements/ingredientmono-1115-serrapeptase.aspx

• Rakhimov MR. "[Anti-inflammatory activity of domestic papain]." Eksp Klin Farmakol. 2001 Jul-Aug;64(4):48-9.

• Rakhimov MR. "[Pharmacological study of papain from the papaya plant cultivated in Uzbekistan]." Eksp Klin Farmakol. 2000 May-Jun;63(3):55-7.

• Gupta OP, Sharma N, Chand D. "A sensitive and relevant model for evaluating anti-inflammatory activity-papaya latex-induced rat paw inflammation." J Pharmacol Toxicol Methods. 1992 Aug;28(1):15-9.

• Udod VM, Kolos AI, Gritsuliak ZN. "[Treatment of patients with lung abscess by local administration of papain]." Vestn Khir Im I I Grek. 1989 Mar;142(3):24-7.

• Chacha PB, Karim SM, Sinniah R, Adaikan PG. "Effect of intra-articular papain, acetylsalicylic acid, indomethacin, prostaglandin and alcohol on the articular cartilage of rabbit knees." Singapore Med J. 1980 Jun;21(3):599-603

• Steffen C, Zeitlhofer J, Menzel J, Smolen J. "[Antigen induced experimental arthritis as a testing method for anti-inflammatory effects of orally administered substances]." Z Rheumatol. 1979 Jul-Aug;38(7-8):264-78. German.

• Guesnier LR, Le Verge R, Trebaul L. "[Lysis by papain of cartilage in the rabbit ear. Comparison of the protective effects of sodium salicylate and arginine salicylate]." Therapie. 1975 Nov-Dec;30(6):931-4. French.

• http://www.webmd.com/vitamins-supplements/ingredientmono-69-papain.aspx

• Sahbaz A, Aynioglu O, Isik H, Ozmen U, Cengil O, Gun BD, Gungorduk K. "Bromelain: a natural proteolytic for intra-abdominal adhesion prevention." Int J Surg. 2015 Feb;14:7-11. doi: 10.1016/j.ijsu.2014.12.024. Epub 2015 Jan 6.

• de la Barrera-Núñez MC, Yáñez-Vico RM, Batista-Cruzado A, Heurtebise-Saavedra JM, Castillo-de Oyagüe R, Torres-Lagares D. "Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period." Med Oral Patol Oral Cir Bucal. 2014 Mar 1;19(2):e157-62.

• Secor ER Jr, Shah SJ, Guernsey LA, Schramm CM, Thrall RS. "Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma." Altern Ther Health Med. 2012 Sep-Oct;18(5):9-17.

• Borrelli F, Capasso R, Severino B, Fiorino F, Aviello G, De Rosa G, Mazzella M, Romano B, Capasso F, Fasolino I, Izzo AA. "Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice." Neurogastroenterol Motil. 2011 Aug;23(8):745-e331. doi: 10.1111/j.1365-2982.2011.01735.x. Epub 2011 Jun 21.

• Hale LP, Chichlowski M, Trinh CT, Greer PK. "Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis." Inflamm Bowel Dis. 2010 Dec;16(12):2012-21. doi: 10.1002/ibd.21320.

• Fitzhugh DJ, Shan S, Dewhirst MW, Hale LP. "Bromelain treatment decreases neutrophil migration to sites of inflammation." Clin Immunol. 2008 Jul;128(1):66-74. doi: 10.1016/j.clim.2008.02.015. Epub 2008 May 14.

• Secor ER, Carson WF, Singh A, Pensa M, Guernsey LA, Schramm CM, Thrall RS. "Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma." Evid Based Complement Alternat Med. 2008 Mar;5(1):61-9. doi: 10.1093/ecam/nel110.

• Onken JE, Greer PK, Calingaert B, Hale LP. "Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro." Clin Immunol. 2008 Mar;126(3):345-52. Epub 2007 Dec 21.

• http://www.webmd.com/vitamins-supplements/ingredientmono-895-bromelain.aspx

• Yike I. "Fungal proteases and their pathophysiological effects." Mycopathologia. 2011 May;171(5):299-323. doi: 10.1007/s11046-010-9386-2. Epub 2011 Jan 23. Review.

• Wichadakul D, Kobmoo N, Ingsriswang S, Tangphatsornruang S, Chantasingh D, Luangsa-Ard JJ, Eurwilaichitr L. "Insights from the genome of Ophiocordyceps polyrhachis-furcata to pathogenicity and host specificity in insect fungi." BMC Genomics. 2015 Oct 28;16(1):881. doi: 10.1186/s12864-015-2101-4.

• Mahajan C, Basotra N, Singh S, Di Falco M, Tsang A, Chadha BS. "Malbranchea cinnamomea: A thermophilic fungal source of catalytically efficient lignocellulolytic glycosyl hydrolases and metal dependent enzymes." Bioresour Technol. 2016 Jan;200:55-63. doi: 10.1016/j.biortech.2015.09.113. Epub 2015 Oct 13.

• Naglot A, Goswami S, Rahman I, Shrimali DD, Yadav KK, Gupta VK, Rabha AJ, Gogoi HK, Veer V. "Antagonistic Potential of Native Trichoderma viride Strain against Potent Tea Fungal Pathogens in North East India." Plant Pathol J. 2015 Sep;31(3):278-89. doi: 10.5423/PPJ.OA.01.2015.0004. Epub 2015 Sep 30.

• de Souza PM, Bittencourt ML, Caprara CC, de Freitas M, de Almeida RP, Silveira D, Fonseca YM, Ferreira Filho EX, Pessoa Junior A, Magalhães PO. "A biotechnology perspective of fungal proteases." Braz J Microbiol. 2015 Jun 1;46(2):337-46. doi: 10.1590/S1517-838246220140359. eCollection 2015 Jun. Review.

• Orlandelli RC, de Almeida TT, Alberto RN, Polonio JC, Azevedo JL, Pamphile JA. "Antifungal and proteolytic activities of endophytic fungi isolated from Piper hispidum Sw." Braz J Microbiol. 2015 Jun 1;46(2):359-66. doi: 10.1590/S1517-838246220131042. eCollection 2015 Jun.

• Chen ZF, Ai LY, Wang JL, Ren LL, Yu YN, Xu J, Chen HY, Yu J, Li M, Qin WX, Ma X, Shen N, Chen YX, Hong J, Fang JY. "Probiotics Clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis." Future Microbiol. 2015 Sep;10:1433-45. doi: 10.2217/fmb.15.66. Epub 2015 Sep 7.

• Zhao L, Lei Y, Bao Y, Jia R, Ma Q, Zhang J, Chen J, Ji C. "Ameliorative effects of Bacillus subtilis ANSB01G on zearalenone toxicosis in pre-pubertal female gilts." Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(4):617-25. doi: 10.1080/19440049.2014.976845. Epub 2014 Nov 19.

• Gu MJ, Song SK, Park SM, Lee IK, Yun CH. "Bacillus subtilis Protects Porcine Intestinal Barrier from Deoxynivalenol via Improved Zonula Occludens-1 Expression." Asian-Australas J Anim Sci. 2014 Apr;27(4):580-6. doi: 10.5713/ajas.2013.13744.

• Jones SE, Paynich ML, Kearns DB, Knight KL. "Protection from intestinal inflammation by bacterial exopolysaccharides." J Immunol. 2014 May 15;192(10):4813-20. doi: 10.4049/jimmunol.1303369. Epub 2014 Apr 16.

• Cerezuela R, Fumanal M, Tapia-Paniagua ST, Meseguer J, Moriñigo MÁ, Esteban MÁ. "Changes in intestinal morphology and microbiota caused by dietary administration of inulin and Bacillus subtilis in gilthead sea bream (Sparus aurata L.) specimens." Fish Shellfish Immunol. 2013 May;34(5):1063-70. doi: 10.1016/j.fsi.2013.01.015. Epub 2013 Feb 9.

• Jeon YL, Yang JJ, Kim MJ, Lim G, Cho SY, Park TS, Suh JT, Park YH, Lee MS, Kim SC, Lee HJ. "Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation." J Med Microbiol. 2012 Dec;61(Pt 12):1766-9. doi: 10.1099/jmm.0.042275-0. Epub 2012 Aug 23.

• http://www.webmd.com/vitamins-supplements/ingredientmono-1185-bacillus%20coagulans.aspx

• Beer AM. "[Naturopathy consultation. Devil's claw and gymnastics for knee and shoulder]." MMW Fortschr Med. 2014 Sep 11;156(15):24.

• Hostanska K, Melzer J, Rostock M, Suter A, Saller R. "Alteration of anti-inflammatory activity of Harpagophytum procumbens (devil's claw) extract after external metabolic activation with S9 mix." J Pharm Pharmacol. 2014 Nov;66(11):1606-14. doi: 10.1111/jphp.12242. Epub 2014 Aug 31.

• Fiebich BL, Muñoz E, Rose T, Weiss G, McGregor GP. "Molecular targets of the antiinflammatory Harpagophytum procumbens (devil's claw): inhibition of TNFα and COX-2 gene expression by preventing activation of AP-1." Phytother Res. 2012 Jun;26(6):806-11. doi: 10.1002/ptr.3636. Epub 2011 Nov 10.

• Sanders M, Grundmann O. "The use of glucosamine, devil's claw (Harpagophytum procumbens), and acupuncture as complementary and alternative treatments for osteoarthritis." Altern Med Rev. 2011 Sep;16(3):228-38

• Denner SS. "A review of the efficacy and safety of devil's claw for pain associated with degenerative musculoskeletal diseases, rheumatoid, and osteoarthritis." Holist Nurs Pract. 2007 Jul-Aug;21(4):203-7

• Brien S, Lewith GT, McGregor G. "Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety." J Altern Complement Med. 2006 Dec;12(10):981-93.

• http://www.webmd.com/vitamins-supplements/ingredientmono-984-devil's%20claw.aspx

• Hsiang CY, Cheng HM, Lo HY, Li CC, Chou PC, Lee YC, Ho TY. "Ginger and Zingerone Ameliorate Lipopolysaccharide-Induced Acute Systemic Inflammation in Mice, Assessed by Nuclear Factor-κB Bioluminescent Imaging." J Agric Food Chem. 2015 Jul 8;63(26):6051-8. doi: 10.1021/acs.jafc.5b01801. Epub 2015 Jun 24.

• Imani H, Tabibi H, Najafi I, Atabak S, Hedayati M, Rahmani L. "Effects of ginger on serum glucose, advanced glycation end products, and inflammation in peritoneal dialysis patients." Nutrition. 2015 May;31(5):703-7. doi: 10.1016/j.nut.2014.11.020. Epub 2014 Dec 20.

• Yang M, Jiang R, Lin X. "[Ginger extracts improve renal injury of high fructose-fed SD rats by inhibiting the expression of proinflammatory cytokines]." Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Sep;30(9):929-32.

• Al-Nahain A, Jahan R, Rahmatullah M. "Zingiber officinale: A Potential Plant against Rheumatoid Arthritis." Arthritis. 2014;2014:159089. doi: 10.1155/2014/159089. Epub 2014 May 27.

• Arablou T, Aryaeian N, Valizadeh M, Sharifi F, Hosseini A, Djalali M. "The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus." Int J Food Sci Nutr. 2014 Jun;65(4):515-20. doi: 10.3109/09637486.2014.880671. Epub 2014 Feb 4.

• Jeena K, Liju VB, Kuttan R. "Antioxidant, anti-inflammatory and antinociceptive activities of essential oil from ginger." Indian J Physiol Pharmacol. 2013 Jan-Mar;57(1):51-62.

• http://www.webmd.com/vitamins-supplements/ingredientmono-961-ginger.aspx

• Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. "Herbal Medicine for Low Back Pain-A Cochrane Review." Spine (Phila Pa 1976). 2015 Nov 30.

• Shara M, Stohs SJ. "Efficacy and Safety of White Willow Bark (Salix alba) Extracts." Phytother Res. 2015 Aug;29(8):1112-6. doi: 10.1002/ptr.5377. Epub 2015 May 22.

• Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. "A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial." Nutr J. 2013 Nov 25;12(1):154. doi: 10.1186/1475-2891-12-154.

• Kong CS, Kim KH, Choi JS, Kim JE, Park C, Jeong JW. "Salicin, an extract from white willow bark, inhibits angiogenesis by blocking the ROS-ERK pathways." Phytother Res. 2014 Aug;28(8):1246-51. doi: 10.1002/ptr.5126. Epub 2014 Feb 17.

• Bucolo C, Marrazzo G, Platania CB, Drago F, Leggio GM, Salomone S. "Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy." J Diabetes Res. 2013;2013:432695. doi: 10.1155/2013/432695. Epub 2013 May 23.

• http://www.webmd.com/vitamins-supplements/ingredientmono-955-willow%20bark.aspx

SHIPPING & RETURNS

We offer the Fastest Shipping & Hassle-Free Returns

Shipping Information

USA Orders

• FREE Shipping for USA orders
• Most US based orders are shipped directly from our warehouse within 24-48 hrs for your convenience and maximum efficiency
• Your product will arrive within 5 to 7 Business Days
• We offer 2 Day Expedited Shipping for $12.99 and 1 Day Priority Shipping for $21.99 no matter how many items you order.

International Orders

• All International (Non-US) orders incur a $9.99 shipping charge
• Orders are shipped via USPS or DHL and may take up to 4 weeks to arrive. Unfortunately we can't control the speed of customs clearance :)
• Please note that goods sent to some countries (e.g. Mexico, Canada, Europe, and the UK) may incur VAT and/or customs duties. These charges are beyond our control and are the responsibility of the customer. Goods shipped to the USA are tax inclusive.

Returns Policy

Our money back guarantee policy lasts 30 days. If 30 days have gone by since your purchase, unfortunately we can’t offer you a refund or exchange.

To complete your return, we require a receipt or proof of purchase.

Once your return is received and inspected, we will send you an email to notify you that we have received your returned item.

When you are approved a credit will automatically be applied to your credit card or original method of payment, within a certain amount of days.

Late or missing refunds (if applicable)

If you haven’t received a refund yet, first check your bank account again.
Then contact your credit card company, it may take some time before your refund is officially posted.

Next contact your bank. There is often some processing time before a refund is posted.

If you’ve done all of this and you still have not received your refund yet, please contact us at support@nutracraft.com.

Sale items (if applicable)

Only regular priced items may be refunded, unfortunately sale items cannot be refunded.

Gifts

If the item was marked as a gift when purchased and shipped directly to you, you’ll receive a gift credit for the value of your return. Once the returned item is received, a gift certificate will be mailed to you.

If the item wasn’t marked as a gift when purchased, or the gift giver had the order shipped to themselves to give to you later, we will send a refund to the gift giver and he will find out about your return.

Shipping

To return your product, you should mail your product to: 400 Hillsboro Technology Drive, Deerfield Beach, FL, 33441

You will be responsible for paying for your own shipping costs for returning your item. Shipping costs are non-refundable. 

Depending on where you live, the time it may take for your exchanged product to reach you, may vary.

If you are shipping an item over $75, you should consider using a trackable shipping service or purchasing shipping insurance. We don’t guarantee that we will receive your returned item.

Product Info

Q. Can I take FlexiAid along with glucosamine and chondroitin sulfate?

A. You can take FlexiAid along with other supplements for joint health. There is no contraindication between FlexiAid ingredients and glucosamine and chondroitin sulfate.

Q. Should I start exercising once I get started on FlexiAid?

A. You can wait until your body gives you the go-ahead to exercise. Working out when the joints are still inflamed can certainly begin to loosen them up, but this means simple exercising such as walking or cycling. Working out with full workouts in the gym needs full support of your joints – but as you improve your flexibility from within by taking the FlexiAid, you will feel that it’s time to exercise. This is the time to go to the gym. Never force yourself to go to the gym to do full workouts when you have joint issues.

Q. Does FlexiAid help me recover quickly after workouts?

A. Yes, the anti-inflammatory action of the ingredients brings in extra circulation to the joints, which in turn flushes out the waste product lactic acid after working out.

Q. How long does it take to have more energy when on FlexiAid?

A. The amount of time it takes to feel more energy varies with each person. Most people can expect to feel a difference after a few days to up to one week.

Q. How large are the capsules? I have trouble with the typical capsule so was wondering about the size.

A. It's fairly large like a Multivitamin. Similar to most vitamins and supplements.

Q. Should I tell my doctor I am taking FlexiAid?

A. It’s always a good idea to mention you are taking herbal supplements, although many doctors may not be well versed in them. However, they may be aware of certain contraindications to the use of some supplement ingredients.

General Questions

Q. Do your products contain Gluten?

A. Many of our products use vegetable capsules and so do not contain gluten. However some of our products are manufactured in a facility that processes other products that contain gluten so we can't guarantee there is no trace of gluten in some products. Please refer to the page for the specific product you are interested in for more information.

Q. Are your products safe to use?

A. Yes, our formulas are made from completely safe ingredients that have shown very little side effects in most users.

Q. Can I get a product for free for an honest review?

A. We usually give away free samples without any obligation when we launch a product just to get the word out there. However, at this time we don't have any units available for free. The best option would be to sign up on our website so we can send you any future giveaways and also get a 20% off code.

We also offer a 100% money-back guarantee, so if you purchase the product and don't get the results you expect then we'll be happy to offer a full refund.

Q. Do you offer any coupon codes?

A. The best way to get special offers and deals is through our Nutracraft Club where we offer 20% off on your first order (one time use) and announce other deals, free offers and provide natural health education.

Q. Can I take your products with prescription medication?

A. Unfortunately, legally, we cannot give you medical advice around taking this product with prescription medicine. So I strongly suggest if you have any questions or concerns about using our product with your current medication or you have a medical condition, then you contact your healthcare professional to see if it will be ok.

Q. Where are your products manufactured?

A. Our products are manufactured in the USA, in a cGMP and FDA registered facility.

Shipping, Guarantee and Support

Q. When will my product arrive?

A. Standard product delivery time is between 3-5 business days from the time of your order. Priority shipping will be 1-2 days depending on the time of order.

Q. Do you ship internationally?

A. Yes we do. International shipping has a flat rate of $14.95 per order and can take 2-3 weeks to arrive.

Q. Do you offer a money back guarantee?

A: Yes, we believe that you should be fully satisfied with your product. We offer a full 60 day money back guarantee. If you are not happy, simply return your bottle and we’ll issue a full refund. This way you can try our products completely risk-free.

Q. Do you have a contact number I can reach you at?

A. Please contact our Customer Support Team at 1-855-377-7444

WHY BUY FROM US

Just like you, we live everyday determined to improve our bodies and quality of life through better life choices, proper nutrition and supplementing with quality herbs, blends, and vitamins. Regardless of your current level of health, you deserve nutritional supplements that you can trust.

You can rest easy knowing that our supplements are formulated by experts using high-quality natural ingredients in a top-of-the-line, FDA registered facility using Good Manufacturing Practices. 

We stand behind all our products and based on the countless testimonials and feedback received we know you will love them too. In fact if you are not 100% satisfied then we’ll give you your money back, it’s that simple!

Along with great products, we have unmatched customer service. If you have a question or issue you want to discuss, give us a call, send us an email. We’ll respond properly. We’ll give you the attention that you deserve.

And lastly, we truly care. We care about you and your health. We go that extra mile to make sure that you're well taken care of through education and great products, fast free shipping, and amazing customer support.

Shop with us today and feel the Nutracraft difference for yourself.

A Few Of The Reasons You Should Buy From Us:

• Premium Quality Formulas - Nutracraft’s products are specifically designed to help improve and encourage your health the natural way. All of our products are made with the highest quality ingredients.
• Free Standard Shipping - We offer free standard shipping on all orders in the USA over $40 so there are no hidden costs at checkout.
• FDA Registered Facility - Nutracraft’s products are produced in state-of-the-art FDA registered facility under current Good Manufacturing Practice standards. This ensures you get quality supplements that you can trust!
• Made in the USA - All of our products are manufactured and tested in the USA. We do not outsource the manufacturing of our products from overseas. All of our products are tested to ensure what is on the label is in the bottle.
• Experienced Product Advisors - We have an experienced board of scientific advisors including Doctor’s, a Naturopath and a Biochemist, who help ensure we create the best products and natural health advice to improve your health.
• 60-Day Money Back Guarantee - Our commitment to quality and health is also why we can offer our risk-free guarantee. We proudly stand behind all of our products. If you’re not completely satisfied, for any reason, just get in touch within 60-days of purchase and we'll give your money back. No questions asked! And absolutely no-hassle!
• Fast Delivery - We use national carriers like DHL, USPS, UPS and more to ship your order fast (usually within 3-5 business days). We have our products strategically placed in warehouses across the United States to ensure your order gets to you fast!
• Secure Ordering – We offer secure credit card processing with SSL encryption. You are safe shopping with us.
• Lowest pricing available online – We manufacture and sell our products direct to the customer so we cut out the middle-man.  That means we can offer the best price for you.
• Courteous and professional support – All messages replied to within 24 hours (usually a lot sooner)
• Tons of satisfied customers – 1000’s of customers have tried our products and keep coming back for more. Will you be one of them?

See for yourself why Nutracraft is a name you can trust and you’ll become one of our many satisfied customers that come back, again and again!